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Alzheimer's disease drug treats traumatic brain injury, report GUMC researchers: (GEORGETOWN UNIV MED SCH)

July 13, 2009

The destructive cellular pathways activated in Alzheimer's disease are also triggered following traumatic brain injury, say researchers from Georgetown University Medical Center (GUMC). They say this finding suggests that novel therapy might successfully target both conditions. In an oral presentation at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease, the scientists will show that deactivating these pathways in part by using a gamma secretase inhibitor - a class of Alzheimer's disease drugs currently being tested - reduced loss of neurons in animal models of traumatic brain injury and protected the animals against motor and cognitive deficits. [click here to view] (http://www.eurekalert.org/pub_releases/2009-07/gumc-add070909.php)

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